Abstract
Background: Diabetes is a metabolic, endocrine disorder that is featured by hyperglycemia and glucose intolerance, primarily due to beta cell destruction, with insulin resistance playing a secondary role. It is treated with the help of many chemical-based drugs as well as natural derivatives.
Objective: There is an urgent need to develop new efficacious, cheaper and more available drugs to face this growing public health challenge. Many anti-diabetic drugs are often associated with many adverse effects.
Materials & Methods: Literature was reviewed in a narrative manner in order to obtain information regarding active phytoactives present in different plants. Anti-diabetic drugs are often loaded with side effects; therefore, this review was carried out for the selection of effective natural therapeutic moieties with less or no adverse effects.
Results: In this review article, we have described the details of recently detected bioactive compounds present in different natural substances which can be used effectively for diabetes-related adversities.
Conclusion: Natural products-based bioactive molecules have been proven to improve insulin resistance and other related complications through suppression of inflammatory signaling pathways.
Keywords: Diabetes, insulin, herbal, phytoactives, potential, natural compounds.
Current Traditional Medicine
Title:A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications
Volume: 7 Issue: 5
Author(s): Pranay Wal*, Ankita Wal, Rashmi Saxena Pal and Priya Singh
Affiliation:
- Institute of Pharmacy , PSIT, Kanpur, 209305,India
Keywords: Diabetes, insulin, herbal, phytoactives, potential, natural compounds.
Abstract:
Background: Diabetes is a metabolic, endocrine disorder that is featured by hyperglycemia and glucose intolerance, primarily due to beta cell destruction, with insulin resistance playing a secondary role. It is treated with the help of many chemical-based drugs as well as natural derivatives.
Objective: There is an urgent need to develop new efficacious, cheaper and more available drugs to face this growing public health challenge. Many anti-diabetic drugs are often associated with many adverse effects.
Materials & Methods: Literature was reviewed in a narrative manner in order to obtain information regarding active phytoactives present in different plants. Anti-diabetic drugs are often loaded with side effects; therefore, this review was carried out for the selection of effective natural therapeutic moieties with less or no adverse effects.
Results: In this review article, we have described the details of recently detected bioactive compounds present in different natural substances which can be used effectively for diabetes-related adversities.
Conclusion: Natural products-based bioactive molecules have been proven to improve insulin resistance and other related complications through suppression of inflammatory signaling pathways.
Export Options
About this article
Cite this article as:
Wal Pranay *, Wal Ankita , Pal Saxena Rashmi and Singh Priya, A Comprehensive Review on Recently Detected Herbal Phytoactives Having Anti-Diabetic Potential for Various Diabetes-Related Complications, Current Traditional Medicine 2021; 7 (5) : e130121190300 . https://dx.doi.org/10.2174/2215083807666210114114334
DOI https://dx.doi.org/10.2174/2215083807666210114114334 |
Print ISSN 2215-0838 |
Publisher Name Bentham Science Publisher |
Online ISSN 2215-0846 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Synthesis, Characterization and Evaluation of Gemfibrozil-Stilbene Hybrid as Antioxidant Agent
Letters in Drug Design & Discovery Transplacental Transfer of Antiretroviral Drugs and Newborn Birth Weight in HIV-Infected Pregnant Women
Current HIV Research Advanced Glycation Endproducts and Diabetes. Beyond Vascular Complications
Endocrine, Metabolic & Immune Disorders - Drug Targets Targeted Metabolomics Reveals Hippurate as a Urinary Potential Marker for Diabetic Nephropathy
Current Metabolomics Editorial: Resolution of Non-Alcoholic-Steatohepatitis. More than One Drug Needed?
Current Vascular Pharmacology The Impact of Inflammatory Profile on Selenium Levels in Hemodialysis Patients
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Cytochrome P450 and Steatosis
Current Drug Metabolism Obesity, Diabetes and Atrial Fibrillation; Epidemiology, Mechanisms and Interventions
Current Cardiology Reviews Acute Toxicity Analysis and Antidiabetic Effect of the Moroccan Spider Flower (<i>Cleome Arabica</i> L.) in Normal and Sreptozotocin-Induced Diabetic Rats
Endocrine, Metabolic & Immune Disorders - Drug Targets Drug Withdrawal and Hyperphagia: Lessons from Tobacco and Other Drugs
Current Pharmaceutical Design Nasal Polyposis: An Overview of Differential Diagnosis and Treatment
Recent Patents on Inflammation & Allergy Drug Discovery The Malignant Obesity Hypoventilation Syndrome (MOHS)
Current Respiratory Medicine Reviews The Role of MicroRNAs in the Pancreatic Differentiation of Pluripotent Stem Cells
MicroRNA The Injured Cochlea as a Target for Inflammatory Processes, Initiation of Cell Death Pathways and Application of Related Otoprotective Strategies
Recent Patents on CNS Drug Discovery (Discontinued) The Effects of Direct Renin Inhibitor, Aliskiren, on Arterial Hypertension, Chronic Kidney Disease and Cardiovascular Disease: Optimal Pharmacotherapy
Cardiovascular & Hematological Agents in Medicinal Chemistry Sensors Based On Carbon Nanotubes and Their Applications: A Review
Current Nanoscience Nutrigenomics and Its Approaches for Control of Chronic Diseases
Current Biotechnology Development and Evaluation of Nateglinide Loaded Polycaprolactone Nanoparticles
Micro and Nanosystems Renal Artery Stenting: Efficacy and Complications
Current Hypertension Reviews Carotenoids and Cardiovascular Risk
Current Pharmaceutical Design