Volume 25, Issue 2
Fluoropyrimidine Toxicity: the Hidden Secrets of DPYD
Pp: 91-95
Author(s): Vangelis G. Manolopoulos and Georgia Ragia*
DOI: 10.2174/0113892002296707240311105527
The Role of CYPs and Transporters in the Biotransformation and Transport of the Anti-hepatitis C Antiviral Agents Asunaprevir, Daclatasvir, and Beclabuvir: Impact of Liver Disease, Race and Drug-drug Interactions on Safety and Efficacy
Pp: 96-109
Author(s): Michael Murray*
DOI: 10.2174/0113892002288832240213095622
Regulation of Gut Microbiota by Herbal Medicines
Pp: 110-127
Author(s): Yogita Shinde* and Gitanjali Deokar
DOI: 10.2174/0113892002287336240328083220
Comparative Analysis of Machine Learning Algorithms Evaluating the Single Nucleotide Polymorphisms of Metabolizing Enzymes with Clinical Outcomes Following Intravenous Paracetamol in Preterm Neonates with Patent Ductus Arteriosus
Pp: 128-139
Author(s): Kannan Sridharan*, George Priya Doss C, Hephzibah Cathryn R, Thirumal Kumar D and Muna Al Jufairi
DOI: 10.2174/0113892002289238240222072027
A Phase I Clinical Study of the Pharmacokinetics and Safety of Prusogliptin Tablets in Subjects with Mild to Moderate Hepatic Insufficiency and Normal Liver Function
Pp: 140-151
Author(s): Huiting Zhang, Yicong Bian, Weifeng Zhao*, Liyan Miao*, Hua Zhang*, Juanjuan Cui, Xiaofang Zhang, Xueyuan Zhang and Wen Cai
DOI: 10.2174/0113892002288120240221111336
Unraveling the Role of COMT Polymorphism in Dopamine-Mediated Vasopressor Effects: An Observational Cross-Sectional Study
Pp: 152-156
Author(s): Kannan Sridharan*, Anfal Jassim, Ali Mohammed Qader and Sheikh Abdul Azeez Pasha
DOI: 10.2174/0113892002293952240315064943
Comparative Analysis of the Gelsemium Alkaloids Metabolism in Human, Pig, Goat, and Rat Liver Microsomes
Pp: 157-163
Author(s): Yi-Rong Wang, Meng-Ting Zuo, Wen-Bo Xu and Zhao-Ying Liu*
DOI: 10.2174/0113892002298633240322071126
The Metabolism of the New Benzodiazepine Remimazolam
Pp: 164-173
Author(s): Wolfgang Schmalix, Karl-Uwe Petersen, Marija Pesic and Thomas Stöhr*
DOI: 10.2174/0113892002301026240318060307
Effects of Clarithromycin and Ketoconazole on FK506 Metabolism in Different CYP3A4 Genotype Recombinant Metabolic Enzyme Systems
Pp: 174-177
Author(s): Jinhua Wen*, Yuwei Xiao, Menghua Zhao, Chen Yang and Weiqiang Hu
DOI: 10.2174/0113892002286019240315052145