Search Result "Client-centered"


Development of Small Molecule Hsp90 Inhibitors: Utilizing Both Forward and Reverse Chemical Genomics for Drug Identification

Journal: Current Medicinal Chemistry
Volume: 10 Issue: 9 Year: 2003 Page: 733-739
Author(s): Len Neckers

Genes and Proteins Governing the Cellular Sensitivity to HSP90 Inhibitors: A Mechanistic Perspective

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 331-341
Author(s): Alison Maloney, Paul A. Clarke, Paul Workman

The C-Terminal Half of Heat Shock Protein 90 Represents a Second Site for Pharmacologic Intervention in Chaperone Function

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 343-347
Author(s): Monica G. Marcu, Leonard M. Neckers

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 377-383
Author(s): Edward A. Sausville, Joseph E. Tomaszewski, Percy Ivy

The WWW as a Tool to Obtain Molecular Parameters

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 3 Issue: 8 Year: 2003 Page: 809-820
Author(s): Igor V. Tetko

The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 349-358
Author(s): Luke Whitesell, Rochelle Bagatell, Ryan Falsey

How Much Gets there and What Does it Do?: The Need for Better Pharmacokinetic and Pharmacodynamic Endpoints in Contemporary Drug Discovery and Development

Journal: Current Pharmaceutical Design
Volume: 9 Issue: 1 Year: 2003 Page: 891-902
Author(s): Paul Workman

Xenopus Informatics

Journal: Current Genomics
Volume: 4 Issue: 8 Year: 2003 Page: 653-664
Author(s): Jeff B. Bowes, Peter D. Vize

Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90

Journal: Current Cancer Drug Targets
Volume: 3 Issue: 5 Year: 2003 Page: 371-376
Author(s): Gabriela Chiosis, Brian Lucas, Henri Huezo, David Solit, Andrea Basso, Neal Rosen

Software Packages for Quantitative Microarray-Based Gene Expression Analysis

Journal: Current Pharmaceutical Biotechnology
Volume: 4 Issue: 6 Year: 2003 Page: 417-437
Author(s): I. M. Gana Dresen, J. Husing, E. Kruse, T. Boes, K.- H. Jockel

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