Search Result "Akt"


Review Article

PI3K/Akt/mTOR Intracellular Pathway and Breast Cancer: Factors, Mechanism and Regulation

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1633-1638
Author(s): Var Ruchi Sharma,Girish Kumar Gupta,A. K. Sharma,Navneet Batra,Daljit K. Sharma,Amit Joshi,Anil K. Sharma

Review Article

PI3K/Akt Pathway: A Potential Therapeutic Target for Chronic Pain

Journal: Current Pharmaceutical Design
Volume: 23 Issue: 1 Year: 2017 Page: 1860-1868
Author(s): Shu-Ping Chen,Ya-Qun Zhou,Dai-Qiang Liu,Wen Zhang,Anne Manyande,Xue-Hai Guan,Yu-ke Tian,Da-Wei Ye,Deeq Mohamed Omar

Review Article

Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer

Journal: Current Medicinal Chemistry
Volume: 24 Issue: 1 Year: 2017 Page: 1321-1331
Author(s): Safieh Ebrahimi,Mina Hosseini,Soodabeh Shahidsales,Mina Maftouh,Gordon A. Ferns,Majid Ghayour-Mobarhan,Seyed Mahdi Hassanian,Amir Avan

Review Article

The PI3K/AKT/mTOR-Signal Transduction Pathway as Drug Target in Triple-Negative Breast Cancer

Journal: Clinical Cancer Drugs
Volume: 4 Issue: 1 Year: 2017 Page: 47-58
Author(s): Jens C. Hahne,Jorg B. Engel,Arnd Honig,Susanne R. Meyer,Domenico Zito,Andrea Lampis,Nicola Valeri

Review Article

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer

Journal: Current Drug Targets
Volume: 18 Issue: 4 Year: 2017 Page: 421-435
Author(s): Nand Kishor Roy,Devivasha Bordoloi,Javadi Monisha,Ganesan Padmavathi,Jibon Kotoky,Ramesh Golla,Ajaikumar B. Kunnumakkara

Research Article

Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway

Journal: Current Cancer Drug Targets
Volume: 17 Issue: 4 Year: 2017 Page: 376-385
Author(s): Ruzhen Zheng,Hao Jiang,Jinhui Li,Xinge Liu,Hongwei Xu

Research Article open access plus

IRS-1 pY612 and Akt-1/PKB pT308 Phosphorylation and Antiinflammatory Effect of Diindolylmethane in Adipocytes Cocultured with Macrophages

Journal: Medicinal Chemistry
Volume: 13 Issue: 8 Year: 2017 Page: 727-733
Author(s): Alfonso Lopez-Vazquez,Jesus J. Garcia-Banuelos,Angelica S. Gonzalez-Garibay,Pedro E. Urzua-Lozano,Susana Del Toro-Arreola,Miriam R. Bueno-Topete,Sergio Sanchez-Enriquez,Jose F. Munoz-Valle,Luis F. Jave-Suarez,Juan Armendariz-Borunda,Blanca E. Bastidas-Ramirez

Research Article

Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway

Journal: CNS & Neurological Disorders - Drug Targets
Volume: 16 Issue: 7 Year: 2017 Page: 828-836
Author(s): Xing-tong Li,Zhang Liang,Tong-tong Wang,Jin-wei Yang,Wei Ma,Shi-kang Deng,Xian-bin Wang,Yun-fei Dai,Jian-hui Guo,Li-yan Li

Research Article

Synthesis and Bioevaluation of Quaternary Centered 3-hydroxy-3 (alkynyl)indolin-2-one Derivatives as Potential Cytotoxic Agents and Akt Kinase Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 1 Year: 2017 Page: 1963-1970
Author(s): P. Sai Prathima,R. Bikshapathi,Y. Poornachandra,V. Himabindu,G. Jagadeesh Kumar,N. Jagadeesh,C. Ganesh Kumar,V. Jayathirtha Rao

Research Article

Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 395-403
Author(s): Chen-Chen Ma,Zhao-Peng Liu

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