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Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 22 Year: 2012 Page: 3748-3762
Author(s): D. A. Altomare,A. R. Khaled

Genistein Potentiates the Anti-cancer Effects of Gemcitabine in Human Osteosarcoma via the Downregulation of Akt and Nuclear Factor-ÎºB Pathway

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 5 Year: 2012 Page: 554-563
Author(s): Chengzhen Liang,Hao Li,Chengchun Shen,Jianbo Lai,Zhongli Shi,Bing Liu,Hui-min Tao

The Quinoline Imidoselenocarbamate EI201 Blocks the AKT/mTOR Pathway and Targets Cancer Stem Cells Leading to a Strong Antitumor Activity

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 1 Year: 2012 Page: 3031-3043
Author(s): E. Ibanez, A. Agliano, C. Prior, P. Nguewa, M. Redrado, I. Gonzalez-Zubeldia, D. Plano, J. A. Palop, C. Sanmartin, A. Calvo

Andrographolide Inhibits Osteopontin Expression and Breast Tumor Growth Through Down Regulation of PI3 Kinase/Akt Signaling Pathway

Journal: Current Molecular Medicine
Volume: 12 Issue: 8 Year: 2012 Page: 952-966
Author(s): S. Kumar,H. S. Patil,P. Sharma,D. Kumar,S. Dasari,V. G. Puranik,H. V. Thulasiram,G. C. Kundu

Recent Developments in Targeted Therapies of the RAF-MEK and PI3KAKT Pathways in Cancer Treatment

Journal: Current Cancer Therapy Reviews
Volume: 8 Issue: 3 Year: 2012 Page: 205-217
Author(s): Lobke G.M. Cremers,Johannes Boonstra

Perspectives on mTOR Inhibitors for Castration-Refractory Prostate Cancer

Journal: Current Cancer Drug Targets
Volume: 12 Issue: 8 Year: 2012 Page: 940-949
Author(s): Salvatore L. Burgio,Francesco Fabbri,Ian J. Seymour,Wainer Zoli,Dino Amadori,Ugo De Giorgi

Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells with Primary Trastuzumab Resistance

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2012 Page: 151-162
Author(s): Sylvia S. Gayle, Samuel L.M. Arnold, Ruth M. ORegan, Rita Nahta

Combination of Valproic Acid and ATRA Restores RARβ2 Expression and Induces Differentiation in Cervical Cancer through the PI3K/Akt Pathway

Journal: Current Molecular Medicine
Volume: 12 Issue: 3 Year: 2012 Page: 342-354
Author(s): D. Feng, Z. Cao, C. Li, L. Zhang, Y. Zhou, J. Ma, R. Liu, H. Zhou, W. Zhao, H. Wei, B. Ling

PDGF Receptor β Signaling in Pericytes Following Ischemic Brain Injury

Journal: Current Neurovascular Research
Volume: 9 Issue: 1 Year: 2012 Page: 1-9
Author(s): Koichi Arimura, Tetsuro Ago, Masahiro Kamouchi, Kuniyuki Nakamura, Koji Ishitsuka, Junya Kuroda, Hiroshi Sugimori, Hiroaki Ooboshi, Tomio Sasaki, Takanari Kitazono

Altered Calmodulin Degradation and Signaling in Non-Neuronal Cells from Alzheimerâs Disease Patients

Journal: Current Alzheimer Research
Volume: 9 Issue: 3 Year: 2012 Page: 267-277
Author(s): Noemi Esteras,Ursula Munoz,Carolina Alquezar,Fernando Bartolome,Felix Bermejo-Pareja,Angeles Martin-Requero

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