Search Result "Akt"


Targeting the AKT Pathway in Glioblastoma

Journal: Current Pharmaceutical Design
Volume: 17 Issue: 2 Year: 2011 Page: 2411-2420
Author(s): Kelli A. McDowell, Gregory J. Riggins, Gary L. Gallia

Recent Development of Anticancer Therapeutics Targeting Akt

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 6 Issue: 1 Year: 2011 Page: 146-159
Author(s): John K. Morrow, Lei Du-Cuny, Lu Chen, Emmanuelle J. Meuillet, Eugene A. Mash, Garth Powis, Shuxing Zhang

Developments in Selective Small Molecule ATP-Targeting the Serine/Threonine Kinase Akt/PKB

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1093-1107
Author(s): P. Wang, L. Zhang, Q. Hao, G. Zhao

Protein Kinase B/AKT and Focal Adhesion Kinase: Two Close Signaling Partners in Cancer

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 993-1002
Author(s): Shouye Wang, Marc D. Basson

Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2727-2742
Author(s): E. J. Meuillet

The Pro-Survival Function of Akt Kinase can be Overridden or Altered to Contribute to Induction of Apoptosis

Journal: Current Cancer Drug Targets
Volume: 11 Issue: 5 Year: 2011 Page: 586-599
Author(s): D. M. Benbrook, C. P. Masamha

Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2715-2726
Author(s): A. M. Martelli, C. Evangelisti, M. Y. Follo, G. Ramazzotti, M. Fini, R. Giardino, L. Manzoli, J. A. McCubrey, L. Cocco

Recent Developments in Anti-Cancer Agents Targeting PI3K, Akt and mTORC1/2

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 6 Issue: 2 Year: 2011 Page: 210-236
Author(s): Rodrigo Dienstmann, Jordi Rodon, Ben Markman, Josep Tabernero

Multiplex Analysis of Cardiac Hypertrophic Signaling: Reduced in vivo Phosphorylation of Glycogen Synthase Kinase-3β and Proline-Rich Akt Substrate (PRAS40)

Journal: Current Signal Transduction Therapy
Volume: 6 Issue: 1 Year: 2011 Page: 65-70
Author(s): Jens R. Larsen, Morten Smerup, Rikke Norregaard, Jane H. Christensen, Kim Sivesgaard, Sara D. Christensen, Karin Christensen, Erik Sloth, Peter Torp, Niels Gregersen, J. Michael Hasenkam

Insulin Decreases Therapeutic Efficacy in Colon Cancer Cell Line HT29 Via the Activation of the PI3K/Akt Pathway

Journal: Current Drug Discovery Technologies
Volume: 8 Issue: 2 Year: 2011 Page: 119-125
Author(s): Jiezhong Chen, Andrew Katsifis, Changhua Hu, Xu-Feng Huang

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