Current Trends of Supercritical Fluid Technology in Pharmaceutical, Nutraceutical and Food Processing Industries

Particles from Gas-Saturated Solutions and Related Methods for Particle Engineering

Author(s): A. R. Sampaio de Sousa and Catarina M. M. Duarte

Pp: 29-40 (12)

Doi: 10.2174/978160805046811001010029

* (Excluding Mailing and Handling)


One of the most promising methods for particle engineering using supercritical fluids is the PGSS – Particles from gas saturated solutions and derived methods. It has been used to micronized drugs and active compounds and to produce composite particles, mainly for pharmaceutical applications, however food applications are starting to arise among experimental work with potential for industrial applications. The morphology and size of the particles obtained is diverse depending on the system used, but they are usually in a micro-nano size range. This chapter presents an overview of the basic principles of the method, several developments that were further undertaken, and a compilation of different examples and systems.

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