New Developments in Medicinal Chemistry

Volume: 1

General Aspects of the Microwave-Assisted Drug Development

Author(s): Peterson de Andrade, Lilian Sibelle Campos Bernardes and Ivone Carvalho

Pp: 114-132 (19)

DOI: 10.2174/978160805127411001010114

* (Excluding Mailing and Handling)

Abstract

Microwaves are a powerful and reliable energy sources that may be adapted to many applications. Since the introduction of microwave-assisted organic synthesis in 1986, the use of microwave irradiation has now introduced a completely new approach to drug discovery. The efficiency of microwave flash-heating chemistry in dramatically reducing reaction times has recently fascinated many pharmaceutical companies, which are incorporating microwave chemistry into their drug development efforts. Thereby, the time saved by using microwaves is important for accelerating traditional organic synthesis or high-speed medicinal chemistry.

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