Chemistry Based on Natural Products for Therapeutic Purposes
Closes 24 September, 2024
Issue Pre-order formJournal: Current Topics in Medicinal Chemistry
Guest editor(s):Dr. Parag Jain
Introduction
The development of new pharmaceuticals for a wide range of medical conditions has long relied on the identification of promising natural products (NPs). There are over sixty percent of cancer, infectious illness, and CNS disease medications that include an NP pharmacophore, according to the Food and Drug Administration. Since NP pharmacophores are the only ones that can pass the blood-brain barrier, they are more common (>80%) in central nervous system medications. More than seventy new medications for a wide range of illnesses, such as pain, dry cough, and opioid addiction, have been discovered as a result of medicinal chemistry investigations into this conventional NP pharmacophore. A stunning example of the power of medicinal chemistry tools is the morphine example, which shows how NP pharmacophores may be used to create a library of bioactive molecules that are simpler yet still effective as treatments.
Keywords
sulfur, chemistry, physiology, molecules