Abstract
Breast cancer is the most common cancer in women worldwide. Several studies have demonstrated the presence of Human papillomavirus (HPV) DNA in breast cancer samples. However, the role of HPV in breast carcinogenesis is not clear, and the interaction mechanisms between this infectious agent and the breast cancer cell need to be more fully clarified. In this article, we discuss the putative roles of HPV infection in breast carcinogenesis.
Keywords: Breast cancer, human papillomavirus (HPV), etiological factor, E6 and E7 oncoproteins, HER2, BRCA1, BRCA2.
Current Molecular Medicine
Title:Putative Mechanisms of Viral Transmission and Molecular Dysregulation of Mammary Epithelial Cells by Human Papillomavirus: Implications for Breast Cancer
Volume: 16 Issue: 7
Author(s): E. G. de Lima, C. M.M. do Amaral, F. C.Q. Peixe, A. P.A.D. Gurgel, J. da Costa Silva Neto and A. C. de Freitas
Affiliation:
Keywords: Breast cancer, human papillomavirus (HPV), etiological factor, E6 and E7 oncoproteins, HER2, BRCA1, BRCA2.
Abstract: Breast cancer is the most common cancer in women worldwide. Several studies have demonstrated the presence of Human papillomavirus (HPV) DNA in breast cancer samples. However, the role of HPV in breast carcinogenesis is not clear, and the interaction mechanisms between this infectious agent and the breast cancer cell need to be more fully clarified. In this article, we discuss the putative roles of HPV infection in breast carcinogenesis.
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Lima G. de E., Amaral M.M. do C., Peixe C.Q. F., Gurgel P.A.D. A., Neto da Costa Silva J. and Freitas C. de A., Putative Mechanisms of Viral Transmission and Molecular Dysregulation of Mammary Epithelial Cells by Human Papillomavirus: Implications for Breast Cancer, Current Molecular Medicine 2016; 16 (7) . https://dx.doi.org/10.2174/1566524016666160805120410
DOI https://dx.doi.org/10.2174/1566524016666160805120410 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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