Abstract
Experimental studies have demonstrated that thalidomide, a drug developed as a sedative, has antitumoral properties. Its broad spectrum of actions besides its antiangiogenic potential, includes immunomodulatory properties, antiinflammatory actions and direct effect on tumor cells and their microenvironment. Multiple myeloma is so far the most responsive malignancy.
Keywords: angiogenesis, antiangiogenesis, multiple myeloma, thalidomide
Letters in Drug Design & Discovery
Title: Thalidomide as an Antiangiogenic Drug in the Treatment of Multiple Myeloma
Volume: 1 Issue: 2
Author(s): Domenico Ribatti and Angelo Vacca
Affiliation:
Keywords: angiogenesis, antiangiogenesis, multiple myeloma, thalidomide
Abstract: Experimental studies have demonstrated that thalidomide, a drug developed as a sedative, has antitumoral properties. Its broad spectrum of actions besides its antiangiogenic potential, includes immunomodulatory properties, antiinflammatory actions and direct effect on tumor cells and their microenvironment. Multiple myeloma is so far the most responsive malignancy.
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Cite this article as:
Ribatti Domenico and Vacca Angelo, Thalidomide as an Antiangiogenic Drug in the Treatment of Multiple Myeloma, Letters in Drug Design & Discovery 2004; 1 (2) . https://dx.doi.org/10.2174/1570180043485491
DOI https://dx.doi.org/10.2174/1570180043485491 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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