Abstract
Recent evidence has suggested improved outcomes following incorporation of intraperitoneal chemotherapy administration with intravenous systemic chemotherapy as first-line treatment of small volume residual epithelial ovarian cancer. This review focuses on the mechanism of actions of the chemotherapeutic drugs and reviews the possible reasons for the superior outcomes of intraperitoneal chemotherapy.
Keywords: Intraperitoneal chemotherapy, cisplatin, carboplatin, paclitaxel, ovarian cancer management
Mini-Reviews in Medicinal Chemistry
Title: Intraperitoneal Chemotherapy as First-Line Treatment in the Management of Epithelial Ovarian Cancer
Volume: 7 Issue: 5
Author(s): S. Rekhraj, J. Kinross, S. Prabhudesai, A. Darzi and P. Ziprin
Affiliation:
Keywords: Intraperitoneal chemotherapy, cisplatin, carboplatin, paclitaxel, ovarian cancer management
Abstract: Recent evidence has suggested improved outcomes following incorporation of intraperitoneal chemotherapy administration with intravenous systemic chemotherapy as first-line treatment of small volume residual epithelial ovarian cancer. This review focuses on the mechanism of actions of the chemotherapeutic drugs and reviews the possible reasons for the superior outcomes of intraperitoneal chemotherapy.
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Rekhraj S., Kinross J., Prabhudesai S., Darzi A. and Ziprin P., Intraperitoneal Chemotherapy as First-Line Treatment in the Management of Epithelial Ovarian Cancer, Mini-Reviews in Medicinal Chemistry 2007; 7 (5) . https://dx.doi.org/10.2174/138955707780619644
DOI https://dx.doi.org/10.2174/138955707780619644 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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