Tissue Distribution and Metabolism of Micro- and Nanoparticles and Medical Implants


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Journal: Current Drug Metabolism
Guest editor(s):Dr. Yajun Shuai

Introduction

With the continuous advancement of modern science and engineering, numerous functional materials and active molecules have been developed and utilized in various industrial, medical, and food applications. Many of these can enter the body, either actively or passively, and have significant and intricate impacts on human health. For example, biomaterials can be actively implanted in the body to repair damaged tissues. Micro/nanoparticles can penetrate tissues through active means, such as drug carriers, or passive means, such as viruses, dust, and microplastics, and can have an impact on health. Therefore, to safely apply these new materials and make accurate clinical predictions, it is necessary to have a comprehensive understanding of their interactions with cells and organisms.

Keywords

biomaterial implants, inhalation, microplastics, biodegradation, gut microbiota, nanotoxicology, pharmacokinetics

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